General Structure Information
| PDB ID | 1hyn |
| HGNC Gene Label(s) | SLC4A1 |
| Structure Name | crystal structure of the cytoplasmic domain of human erythrocyte band-3 protein |
| Resolution | 2.6Å |
| Reference | AUTH D.ZHANG,A.KIYATKIN,J.T.BOLIN,P.S.LOWTITL CRYSTALLOGRAPHIC STRUCTURE AND FUNCTIONALTITL 2 INTERPRETATION OF THE CYTOPLASMIC DOMAIN OFTITL 3 ERYTHROCYTE MEMBRANE BAND 3.REF BLOOD V. 96 2925 2000REFN ISSN 0006-4971PMID 11049968 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 293 |
| Number Of SNVs | 77 |
| Number Of Permutations | 31049 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.137 |
| p-value | 0.127 |
ClinVar
| Number Of Residues | 293 |
| Number Of SNVs | 4 |
| Number Of Permutations | 599 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.0 |
| p-value | 0.306 |
COSMIC
| Number Of Residues | 293 |
| Number Of SNVs | 9 |
| Number Of Permutations | 600 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.028 |
| p-value | 0.009 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.257 |
| p-value | 0.103 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.141 |
| p-value | 0.076 |