General Structure Information
| PDB ID | 2a01 |
| HGNC Gene Label(s) | APOA1 |
| Structure Name | crystal structure of lipid-free human apolipoprotein a-i |
| Resolution | 2.4Å |
| Reference | AUTH A.A.AJEES,G.M.ANANTHARAMAIAH,V.K.MISHRA,AUTH 2 M.M.HUSSAIN,K.H.M.MURTHYTITL CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I:TITL 2 INSIGHTS INTO ITS PROTECTIVE EFFECT AGAINSTTITL 3 CARDIOVASCULAR DISEASES.REF PROC.NATL.ACAD.SCI.USA V. 103 2126 2006REFN ISSN 0027-8424PMID 16452169DOI 10.1073/PNAS.0506877103 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 243 |
| Number Of SNVs | 68 |
| Number Of Permutations | 18014 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.055 |
| p-value | 0.564 |
ClinVar
| Number Of Residues | 243 |
| Number Of SNVs | 16 |
| Number Of Permutations | 4732 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.033 |
| p-value | 0.697 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of ClinVar SNVs | 16 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.012 |
| p-value | 0.607 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
