2ILA.A | IL1A – ASTRID

2ILA.A | IL1A

PDB ID	2ila
HGNC Gene Label(s)	IL1A
Structure Name	structure of interleukin 1alpha at 2.7-angstroms resolution
Resolution	2.3Å
Reference	AUTH B.J.GRAVES,M.H.HATADA,W.A.HENDRICKSON,J.K.MILLER,AUTH 2 V.S.MADISON,Y.SATOWTITL STRUCTURE OF INTERLEUKIN 1 ALPHA AT 2.7-ATITL 2 RESOLUTION.REF BIOCHEMISTRY V. 29 2679 1990REFN ISSN 0006-2960PMID 2346741DOI 10.1021/BI00463A009

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:113537190	rs17562	N>D	A:9	(7.75, 52.21, 38.51)
2:113537176	rs370144723	I>M	A:13	(15.99, 54.98, 29.97)
2:113537151	rs3783581	D>N	A:22	(10.93, 74.56, 20.85)
2:113537141	rs190193834	N>S	A:25	(13.82, 76.46, 17.12)
2:113537137		Q>H	A:26	(15.25, 77.70, 20.43)
2:113537126	rs201678238	R>Q	A:30	(20.96, 76.18, 31.42)
2:113537113		Q>H	A:34	(18.50, 75.22, 38.96)
2:113537111		Y>C	A:35	(16.69, 76.69, 35.85)
2:113537105	rs376874217	T>M	A:37	(15.80, 78.96, 29.42)
2:113537103		A>P	A:38	(15.42, 78.62, 25.69)
2:113537096		A>E	A:40	(18.22, 80.15, 19.57)
2:113535677		M>V	A:52	(14.45, 60.41, 29.11)
2:113535667	rs140612680	Y>C	A:55	(7.82, 54.77, 34.00)
2:113535662		S>T	A:57	(1.48, 53.38, 36.10)
2:113535658		S>L	A:58	(-0.18, 51.20, 38.76)
2:113535640	rs151111351	I>N	A:64	(3.54, 57.11, 28.23)
2:113535623		I>V	A:70	(20.21, 66.22, 32.20)
2:113535602	rs547288438	V>M	A:77	(13.52, 68.38, 35.97)
2:113535579	rs148393309	Q>H	A:84	(6.49, 79.06, 38.00)
2:113535565		K>R	A:89	(16.51, 68.85, 41.43)
2:113532835	rs144254850	E>K	A:93	(19.95, 57.80, 41.70)
2:113532816		T>I	A:99	(4.40, 58.18, 44.12)
2:113532775	COSM441011	G>S	A:113	(3.99, 64.24, 13.93)
2:113532771		T>I	A:114	(7.29, 65.95, 14.89)
2:113532772	rs368867049	T>A	A:114	(7.29, 65.95, 14.89)
2:113532765		N>T	A:116	(6.28, 66.69, 21.32)
2:113532742		P>S	A:124	(-2.16, 67.51, 33.97)
2:113532678		I>T	A:145	(5.28, 77.78, 23.24)