General Structure Information
| PDB ID | 2hdl |
| HGNC Gene Label(s) | CXCL14 |
| Structure Name | solution structure of brak/cxcl14 |
| Resolution | -1.0Å |
| Reference | AUTH F.C.PETERSON,J.A.THORPE,A.G.HARDER,B.F.VOLKMAN,AUTH 2 S.R.SCHWARZETITL STRUCTURAL DETERMINANTS INVOLVED IN THE REGULATIONTITL 2 OF CXCL14/BRAK EXPRESSION BY THE 26 S PROTEASOME.REF J.MOL.BIOL. V. 363 813 2006REFN ISSN 0022-2836PMID 16987528DOI 10.1016/J.JMB.2006.08.057 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 77 |
| Number Of SNVs | 16 |
| Number Of Permutations | 1789 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.97 |
COSMIC
| Number Of Residues | 77 |
| Number Of SNVs | 4 |
| Number Of Permutations | 610 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 0.865 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.192 |
| p-value | 0.918 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
