General Structure Information
| PDB ID | 1lhw |
| HGNC Gene Label(s) | SHBG |
| Structure Name | crystal structure of the n-terminal lg-domain of shbg in complex with 2-methoxyestradiol |
| Resolution | 1.75Å |
| Reference | AUTH G.V.AVVAKUMOV,I.GRISHKOVSKAYA,Y.A.MULLER,AUTH 2 G.L.HAMMONDTITL CRYSTAL STRUCTURE OF HUMAN SEX HORMONE-BINDINGTITL 2 GLOBULIN IN COMPLEX WITH 2-METHOXYESTRADIOLTITL 3 REVEALS THE MOLECULAR BASIS FOR HIGH AFFINITYTITL 4 INTERACTIONS WITH C-2 DERIVATIVES OF ESTRADIOL.REF J.BIOL.CHEM. V. 277 45219 2002REFN ISSN 0021-9258PMID 12228253DOI 10.1074/JBC.M207762200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 174 |
| Number Of SNVs | 57 |
| Number Of Permutations | 15964 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.03 |
| p-value | 0.564 |