General Structure Information
| PDB ID | 4g0n |
| HGNC Gene Label(s) | RAF1 |
| Structure Name | crystal structure of wt h-ras-gppnhp bound to the rbd of raf kinase |
| Resolution | 2.45Å |
| Reference | AUTH S.K.FETICS,H.GUTERRES,B.M.KEARNEY,G.BUHRMAN,B.MA,R.NUSSINOV,AUTH 2 C.MATTOSTITL ALLOSTERIC EFFECTS OF THE ONCOGENIC RASQ61L MUTANT ONTITL 2 RAF-RBD.REF STRUCTURE V. 23 505 2015REFN ISSN 0969-2126PMID 25684575DOI 10.1016/J.STR.2014.12.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 78 |
| Number Of SNVs | 11 |
| Number Of Permutations | 2128 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.127 |
| p-value | 0.578 |
COSMIC
| Number Of Residues | 78 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.667 |
| p-value | 0.798 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
