General Structure Information
| PDB ID | 3bt1 |
| HGNC Gene Label(s) | PLAU |
| Structure Name | structure of urokinase receptor, urokinase and vitronectin complex |
| Resolution | 2.8Å |
| Reference | AUTH Q.HUAI,A.ZHOU,L.LIN,A.P.MAZAR,G.C.PARRY,J.CALLAHAN,D.E.SHAW,AUTH 2 B.FURIE,B.C.FURIE,M.HUANGTITL CRYSTAL STRUCTURES OF TWO HUMAN VITRONECTIN, UROKINASE ANDTITL 2 UROKINASE RECEPTOR COMPLEXESREF NAT.STRUCT.MOL.BIOL. V. 15 422 2008REFN ISSN 1545-9993PMID 18376415DOI 10.1038/NSMB.1404 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 125 |
| Number Of SNVs | 26 |
| Number Of Permutations | 3674 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.123 |
| p-value | 0.172 |
COSMIC
| Number Of Residues | 125 |
| Number Of SNVs | 3 |
| Number Of Permutations | 208 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 26 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | -0.362 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
