General Structure Information
| PDB ID | 3uo9 |
| HGNC Gene Label(s) | GLS |
| Structure Name | crystal structure of human gac in complex with glutamate and bptes |
| Resolution | 2.3Å |
| Reference | AUTH B.DELABARRE,S.GROSS,C.FANG,Y.GAO,A.JHA,F.JIANG,J.SONG J,AUTH 2 W.WEI,J.B.HUROVTITL FULL-LENGTH HUMAN GLUTAMINASE IN COMPLEX WITH AN ALLOSTERICTITL 2 INHIBITOR.REF BIOCHEMISTRY V. 50 10764 2011REFN ISSN 0006-2960PMID 22049910DOI 10.1021/BI201613D |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 408 |
| Number Of SNVs | 34 |
| Number Of Permutations | 28212 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.053 |
| p-value | 0.89 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.113 |
| p-value | 0.909 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
