General Structure Information
| PDB ID | 2q3e |
| HGNC Gene Label(s) | UGDH |
| Structure Name | structure of human udp-glucose dehydrogenase complexed with nadh and udp-glucose |
| Resolution | 2.0Å |
| Reference | AUTH S.EGGER,A.CHAIKUAD,K.L.KAVANAGH,U.OPPERMANN,B.NIDETZKYTITL STRUCTURE AND MECHANISM OF HUMAN UDP-GLUCOSETITL 2 6-DEHYDROGENASE.REF J.BIOL.CHEM. V. 286 23877 2011REFN ISSN 0021-9258PMID 21502315DOI 10.1074/JBC.M111.234682 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 460 |
| Number Of SNVs | 80 |
| Number Of Permutations | 47751 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.101 |
| p-value | 0.202 |
COSMIC
| Number Of Residues | 460 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1779 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.238 |
| p-value | 0.203 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 80 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 39.0 |
| K Statistic | -0.253 |
| p-value | 0.939 |