3N7P.D | RAMP1

General Structure Information

PDB ID 3n7p
HGNC Gene Label(s) RAMP1
Structure Name crystal structure of the ectodomain complex of the cgrp receptor, a class-b gpcr, reveals the site of drug antagonism
Resolution 2.8Å
Reference AUTH E.TER HAAR,C.M.KOTH,N.ABDUL-MANAN,L.SWENSON,J.T.COLL,AUTH 2 J.A.LIPPKE,C.A.LEPRE,M.GARCIA-GUZMAN,J.M.MOORETITL CRYSTAL STRUCTURE OF THE ECTODOMAIN COMPLEX OF THE CGRPTITL 2 RECEPTOR, A CLASS-B GPCR, REVEALS THE SITE OF DRUGTITL 3 ANTAGONISM.REF STRUCTURE V. 18 1083 2010REFN ISSN 0969-2126PMID 20826335DOI 10.1016/J.STR.2010.05.014

Variant Set Distributions

ExAC Variants

Number Of Residues 90
Number Of SNVs 32
Number Of Permutations 17452
Optimal Distance Threshold 9.0
K Statistic 0.133
p-value 0.809

Mapped Variants

[+] ExAC Missense Variants