General Structure Information
| PDB ID | 1yck |
| HGNC Gene Label(s) | PGLYRP1 |
| Structure Name | crystal structure of human peptidoglycan recognition protein (pgrp-s) |
| Resolution | 1.7Å |
| Reference | AUTH R.GUAN,Q.WANG,E.J.SUNDBERG,R.A.MARIUZZATITL CRYSTAL STRUCTURE OF HUMAN PEPTIDOGLYCANTITL 2 RECOGNITION PROTEIN S (PGRP-S) AT 1.70 ATITL 3 RESOLUTION.REF J.MOL.BIOL. V. 347 683 2005REFN ISSN 0022-2836PMID 15769462DOI 10.1016/J.JMB.2005.01.070 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 167 |
| Number Of SNVs | 49 |
| Number Of Permutations | 2706 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.059 |
| p-value | 0.814 |
COSMIC
| Number Of Residues | 167 |
| Number Of SNVs | 3 |
| Number Of Permutations | 141 |
| Optimal Distance Threshold | 36.0 |
| K Statistic | 0.667 |
| p-value | 0.015 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.532 |
| p-value | 0.051 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

