General Structure Information
| PDB ID | 2gh0 |
| HGNC Gene Label(s) | GFRA3 |
| Structure Name | growth factor/receptor complex |
| Resolution | 1.92Å |
| Reference | AUTH X.WANG,R.H.BALOH,J.MILBRANDT,K.C.GARCIATITL STRUCTURE OF ARTEMIN COMPLEXED WITH ITS RECEPTOR GFRALPHA3:TITL 2 CONVERGENT RECOGNITION OF GLIAL CELL LINE-DERIVEDTITL 3 NEUROTROPHIC FACTORS.REF STRUCTURE V. 14 1083 2006REFN ISSN 0969-2126PMID 16765900DOI 10.1016/J.STR.2006.05.010 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 200 |
| Number Of SNVs | 31 |
| Number Of Permutations | 14303 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.062 |
| p-value | 0.004 |
COSMIC
| Number Of Residues | 200 |
| Number Of SNVs | 4 |
| Number Of Permutations | 222 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.044 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
