1FJ2.A | LYPLA1

General Structure Information

PDB ID 1fj2
HGNC Gene Label(s) LYPLA1
Structure Name crystal structure of the human acyl protein thioesterase 1 at 1.5 a resolution
Resolution 1.5Å
Reference AUTH Y.DEVEDJIEV,Z.DAUTER,S.R.KUZNETSOV,T.L.JONES,Z.S.DEREWENDATITL CRYSTAL STRUCTURE OF THE HUMAN ACYL PROTEIN THIOESTERASE ITITL 2 FROM A SINGLE X-RAY DATA SET TO 1.5 A.REF STRUCTURE FOLD.DES. V. 8 1137 2000REFN ISSN 0969-2126PMID 11080636DOI 10.1016/S0969-2126(00)00529-3

Variant Set Distributions

ExAC Variants

Number Of Residues 224
Number Of SNVs 48
Number Of Permutations 17487
Optimal Distance Threshold 16.0
K Statistic 0.228
p-value 0.102
COSMIC

Number Of Residues 224
Number Of SNVs 5
Number Of Permutations 302
Optimal Distance Threshold 15.0
K Statistic 0.1
p-value 0.709

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 48
Number Of COSMIC SNVs 5
Optimal Distance Threshold 18.0
K Statistic 0.304
p-value 0.378

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants