General Structure Information
| PDB ID | 3qyb |
| HGNC Gene Label(s) | TBC1D4 |
| Structure Name | x-ray crystal structure of human tbc1d4 (as160) rabgap domain |
| Resolution | 3.5Å |
| Reference | AUTH S.Y.PARK,W.JIN,J.R.WOO,S.E.SHOELSONTITL CRYSTAL STRUCTURES OF HUMAN TBC1D1 AND TBC1D4 (AS160)TITL 2 RABGTPASE-ACTIVATING PROTEIN (RABGAP) DOMAINS REVEALTITL 3 CRITICAL ELEMENTS FOR GLUT4 TRANSLOCATION.REF J.BIOL.CHEM. V. 286 18130 2011REFN ISSN 0021-9258PMID 21454505DOI 10.1074/JBC.M110.217323 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 295 |
| Number Of SNVs | 60 |
| Number Of Permutations | 7428 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.141 |
| p-value | 0.048 |
COSMIC
| Number Of Residues | 295 |
| Number Of SNVs | 3 |
| Number Of Permutations | 205 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.293 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.471 |
| p-value | 0.253 |