General Structure Information
| PDB ID | 2rpc |
| HGNC Gene Label(s) | ZIC3 |
| Structure Name | solution structure of the tandem zf-c2h2 domains from the human zinc finger protein zic 3 |
| Resolution | -1.0Å |
| Reference | AUTH M.HATAYAMA,T.TOMIZAWA,K.SAKAI-KATO,P.BOUVAGNET,AUTH 2 S.KOSE,N.IMAMOTO,S.YOKOYAMA,N.UTSUNOMIYA-TATE,AUTH 3 K.MIKOSHIBA,T.KIGAWA,J.ARUGATITL FUNCTIONAL AND STRUCTURAL BASIS OF THE NUCLEARTITL 2 LOCALIZATION SIGNAL IN THE ZIC3 ZINC FINGER DOMAINREF HUM.MOL.GENET. V. 17 3459 2008REFN ISSN 0964-6906PMID 18716025DOI 10.1093/HMG/DDN239 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 142 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1791 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.036 |
| p-value | 0.428 |
ClinVar
| Number Of Residues | 142 |
| Number Of SNVs | 3 |
| Number Of Permutations | 228 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.667 |
| p-value | 0.022 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 8 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.631 |
| p-value | 0.049 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
