2JGC.A | EIF4E2

PDB ID	2jgc
HGNC Gene Label(s)	EIF4E2
Structure Name	structure of the human eif4e homologous protein, 4ehp without ligand bound
Resolution	2.4Å
Reference	AUTH P.ROSETTANI,S.KNAPP,M.G.VISMARA,L.RUSCONI,AUTH 2 A.D.CAMERONTITL STRUCTURES OF THE HUMAN EIF4E HOMOLOGOUS PROTEIN,TITL 2 H4EHP, IN ITS M(7)GTP-BOUND AND UNLIGANDED FORMS.REF J.MOL.BIOL. V. 368 691 2007REFN ISSN 0022-2836PMID 17368478DOI 10.1016/J.JMB.2007.02.019

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:233422612	rs370882938	A>T	A:52	(-9.80, -28.11, 11.83)
2:233422621		P>S	A:55	(-10.36, -20.76, 7.11)
2:233422634		N>S	A:59	(-6.90, -12.05, 10.21)
2:233422636	rs367941662	Y>H	A:60	(-11.59, -9.67, 10.37)
2:233422639		T>A	A:61	(-9.36, -6.72, 15.20)
2:233422666		G>S	A:70	(-17.98, 16.85, 21.32)
2:233422718	rs554396964	T>N	A:87	(-7.17, -11.17, 16.72)
2:233428981		S>G	A:99	(-20.01, -16.02, 22.41)
2:233428987	rs376155648	M>V	A:101	(-18.84, -9.81, 23.16)
2:233428993	rs142409429	R>C	A:103	(-26.41, -9.33, 22.41)
2:233429040		E>D	A:118	(-4.99, -8.05, 11.29)
2:233429045	rs373307064	I>T	A:120	(-7.32, -1.60, 9.15)
2:233431546		A>E	A:128	(-7.10, 2.23, 4.41)
2:233431558		G>D	A:132	(-13.00, 6.89, 2.11)
2:233431582	COSM1017848	R>Q	A:140	(-36.38, 0.95, 16.12)
2:233431599		R>C	A:146	(-31.94, -9.57, 15.44)
2:233431600	rs572423747	R>H	A:146	(-31.94, -9.57, 15.44)
2:233431624		A>V	A:154	(-21.49, -10.85, 5.80)
2:233431626		M>V	A:155	(-17.67, -8.50, 6.85)
2:233431651	rs371244654	G>E	A:163	(-12.56, -7.15, -2.88)
2:233431668		A>S	A:169	(-17.58, -2.46, 11.14)
2:233431681	rs541446786	V>A	A:173	(-24.49, 3.16, 21.50)
2:233431818		A>P	A:187	(-15.40, 6.82, -2.18)
2:233431839		A>T	A:194	(-23.39, 0.23, -4.95)
2:233431869		L>F	A:204	(-29.52, -6.07, 7.03)
2:233433674	rs565444213	P>S	A:229	(-29.24, 24.74, 19.96)
2:233433680	rs140152833	R>G	A:231	(-26.65, 16.97, 19.25)
2:233433682		R>S	A:231	(-26.65, 16.97, 19.25)

2JGC.A | EIF4E2.