General Structure Information
| PDB ID | 3g65 |
| HGNC Gene Label(s) | HUS1 |
| Structure Name | crystal structure of the human rad9-rad1-hus1 dna damage checkpoint complex |
| Resolution | 2.9Å |
| Reference | AUTH A.S.DORE,M.L.KILKENNY,N.J.RZECHORZEK,L.H.PEARLTITL CRYSTAL STRUCTURE OF THE RAD9-RAD1-HUS1 DNA DAMAGETITL 2 CHECKPOINT COMPLEX–IMPLICATIONS FOR CLAMP LOADING ANDTITL 3 REGULATION.REF MOL.CELL V. 34 735 2009REFN ISSN 1097-2765PMID 19446481DOI 10.1016/J.MOLCEL.2009.04.027 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 258 |
| Number Of SNVs | 74 |
| Number Of Permutations | 15668 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.032 |
| p-value | 0.627 |
COSMIC
| Number Of Residues | 258 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.667 |
| p-value | 0.158 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

