General Structure Information
| PDB ID | 1x2q |
| HGNC Gene Label(s) | STAM2 |
| Structure Name | solution structure of the sh3 domain of the signal transducing adaptor molecule 2 |
| Resolution | -1.0Å |
| Reference | AUTH E.CHIKAYAMA,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THE SIGNALTITL 2 TRANSDUCING ADAPTOR MOLECULE 2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 75 |
| Number Of SNVs | 14 |
| Number Of Permutations | 4943 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.022 |
| p-value | 0.567 |
COSMIC
| Number Of Residues | 75 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.437 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 14 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.267 |
| p-value | 0.597 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
