General Structure Information
| PDB ID | 2i3y |
| HGNC Gene Label(s) | GPX5 |
| Structure Name | crystal structure of human glutathione peroxidase 5 |
| Resolution | 2.0Å |
| Reference | AUTH K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 5REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 188 |
| Number Of SNVs | 53 |
| Number Of Permutations | 34753 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.033 |
| p-value | 0.752 |
COSMIC
| Number Of Residues | 188 |
| Number Of SNVs | 7 |
| Number Of Permutations | 314 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.095 |
| p-value | 0.824 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.067 |
| p-value | 0.92 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
