General Structure Information
| PDB ID | 1d4t |
| HGNC Gene Label(s) | SH2D1A |
| Structure Name | crystal structure of the xlp protein sap in complex with a slam peptide |
| Resolution | 1.1Å |
| Reference | AUTH F.POY,M.B.YAFFE,J.SAYOS,K.SAXENA,M.MORRA,J.SUMEGI,AUTH 2 L.C.CANTLEY,C.TERHORST,M.J.ECKTITL CRYSTAL STRUCTURES OF THE XLP PROTEIN SAP REVEAL ATITL 2 CLASS OF SH2 DOMAINS WITH EXTENDED,TITL 3 PHOSPHOTYROSINE-INDEPENDENT SEQUENCE RECOGNITION.REF MOL.CELL V. 4 555 1999REFN ISSN 1097-2765PMID 10549287DOI 10.1016/S1097-2765(00)80206-3 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 104 |
| Number Of SNVs | 7 |
| Number Of Permutations | 412 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.0 |
| p-value | 0.021 |
ClinVar
| Number Of Residues | 104 |
| Number Of SNVs | 4 |
| Number Of Permutations | 168 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.863 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 7 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.0 |
| p-value | 0.4 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
