General Structure Information
| PDB ID | 3dal |
| HGNC Gene Label(s) | PRDM1 |
| Structure Name | methyltransferase domain of human pr domain-containing protein 1 |
| Resolution | 1.65Å |
| Reference | AUTH H.ZENG,M.F.AMAYA,T.ANTOSHENKO,A.DONG,P.LOPPNAU,AUTH 2 A.BOCHKAREV,J.MIN,A.N.PLOTNIKOV,H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN PR DOMAIN-CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 169 |
| Number Of SNVs | 36 |
| Number Of Permutations | 15740 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.208 |
COSMIC
| Number Of Residues | 169 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2774 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.133 |
| p-value | 0.081 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.233 |
| p-value | 0.171 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
