General Structure Information
| PDB ID | 2l0t |
| HGNC Gene Label(s) | STAM2 |
| Structure Name | solution structure of the complex of ubiquitin and the vhs domain of stam2 |
| Resolution | -1.0Å |
| Reference | AUTH A.LANGE,D.HOELLER,H.WIENK,O.MARCILLAT,J.M.LANCELIN,O.WALKERTITL NMR REVEALS A DIFFERENT MODE OF BINDING OF THE STAM2 VHSTITL 2 DOMAIN TO UBIQUITIN AND DIUBIQUITIN.REF BIOCHEMISTRY V. 50 48 2011REFN ISSN 0006-2960PMID 21121635DOI 10.1021/BI101594A |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 150 |
| Number Of SNVs | 44 |
| Number Of Permutations | 27751 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.327 |
| p-value | 0.221 |
COSMIC
| Number Of Residues | 150 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 44 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.146 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
