General Structure Information
| PDB ID | 2ytx |
| HGNC Gene Label(s) | CSDE1 |
| Structure Name | solution structure of the second cold-shock domain of the human kiaa0885 protein (unr protein) |
| Resolution | -1.0Å |
| Reference | AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,AUTH 2 S.WATANABE,T.HARADA,A.TANAKA,O.OHARA,T.KIGAWA,S.YOKOYAMATITL THE NMR SOLUTION STRUCTURES OF THE FIVE CONSTITUENTTITL 2 COLD-SHOCK DOMAINS (CSD) OF THE HUMAN UNR (UPSTREAM OFTITL 3 N-RAS) PROTEIN.REF J.STRUCT.FUNCT.GENOM. V. 11 181 2010REFN ISSN 1345-711XPMID 20213426DOI 10.1007/S10969-010-9081-Z |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 84 |
| Number Of SNVs | 11 |
| Number Of Permutations | 1775 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.145 |
| p-value | 0.301 |
COSMIC
| Number Of Residues | 84 |
| Number Of SNVs | 3 |
| Number Of Permutations | 71 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.333 |
| p-value | 0.317 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 11 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.455 |
| p-value | 0.127 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

