General Structure Information
| PDB ID | 1olm |
| HGNC Gene Label(s) | SEC14L2 |
| Structure Name | supernatant protein factor in complex with rrr-alpha-tocopherylquinone: a link between oxidized vitamin e and cholesterol biosynthesis |
| Resolution | 1.95Å |
| Reference | AUTH A.STOCKER,U.BAUMANNTITL SUPERNATANT PROTEIN FACTOR IN COMPLEX WITHTITL 2 RRR-ALPHA-TOCOPHERYLQUINONE: A LINK BETWEENTITL 3 OXIDIZED VITAMIN E AND CHOLESTEROL BIOSYNTHESISREF J.MOL.BIOL. V. 332 759 2003REFN ISSN 0022-2836PMID 12972248DOI 10.1016/S0022-2836(03)00924-0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 397 |
| Number Of SNVs | 92 |
| Number Of Permutations | 23589 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.027 |
| p-value | 0.312 |
COSMIC
| Number Of Residues | 397 |
| Number Of SNVs | 3 |
| Number Of Permutations | 266 |
| Optimal Distance Threshold | 39.0 |
| K Statistic | 0.333 |
| p-value | 0.529 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 92 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | -0.564 |
| p-value | 0.118 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
