General Structure Information
| PDB ID | 2cv5 |
| HGNC Gene Label(s) | HIST1H2BK |
| Structure Name | crystal structure of human nucleosome core particle |
| Resolution | 2.5Å |
| Reference | AUTH Y.TSUNAKA,N.KAJIMURA,S.TATE,K.MORIKAWATITL ALTERATION OF THE NUCLEOSOMAL DNA PATH IN THETITL 2 CRYSTAL STRUCTURE OF A HUMAN NUCLEOSOME CORETITL 3 PARTICLEREF NUCLEIC ACIDS RES. V. 33 3424 2005REFN ISSN 0305-1048PMID 15951514DOI 10.1093/NAR/GKI663 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 96 |
| Number Of SNVs | 4 |
| Number Of Permutations | 326 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.0 |
| p-value | 0.687 |
COSMIC
| Number Of Residues | 96 |
| Number Of SNVs | 3 |
| Number Of Permutations | 74 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 0.793 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.333 |
| p-value | 0.401 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
