1W1H.C | PDPK1

General Structure Information

PDB ID 1w1h
HGNC Gene Label(s) PDPK1
Structure Name crystal structure of the pdk1 pleckstrin homology (ph) domain
Resolution 1.45Å
Reference AUTH D.KOMANDER,A.FAIRSERVICE,M.DEAK,G.S.KULAR,AUTH 2 A.R.PRESCOTT,C.P.DOWNES,S.T.SAFRANY,D.R.ALESSI,AUTH 3 D.M.F.VAN AALTENTITL STRUCTURAL INSIGHTS INTO THE REGULATION OF PDK1 BYTITL 2 PHOSPHOINOSITIDES AND INOSITOL PHOSPHATESREF EMBO J. V. 23 3918 2004REFN ISSN 0261-4189PMID 15457207DOI 10.1038/SJ.EMBOJ.7600379

Variant Set Distributions

ExAC Variants

Number Of Residues 138
Number Of SNVs 21
Number Of Permutations 7384
Optimal Distance Threshold 12.0
K Statistic 0.105
p-value 0.024

Mapped Variants

[+] ExAC Missense Variants