General Structure Information
| PDB ID | 2fic |
| HGNC Gene Label(s) | BIN1 |
| Structure Name | the crystal structure of the bar domain from human bin1/amphiphysin ii and its implications for molecular recognition |
| Resolution | 1.99Å |
| Reference | AUTH E.CASAL,L.FEDERICI,W.ZHANG,J.FERNANDEZ-RECIO,E.M.PRIEGO,AUTH 2 R.N.MIGUEL,J.B.DUHADAWAY,G.C.PRENDERGAST,B.F.LUISI,E.D.LAUETITL THE CRYSTAL STRUCTURE OF THE BAR DOMAIN FROM HUMANTITL 2 BIN1/AMPHIPHYSIN II AND ITS IMPLICATIONS FOR MOLECULARTITL 3 RECOGNITIONREF BIOCHEMISTRY V. 45 12917 2006REFN ISSN 0006-2960PMID 17059209DOI 10.1021/BI060717K |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 201 |
| Number Of SNVs | 41 |
| Number Of Permutations | 16606 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.037 |
| p-value | 0.094 |
COSMIC
| Number Of Residues | 201 |
| Number Of SNVs | 3 |
| Number Of Permutations | 377 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.845 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 52.0 |
| K Statistic | -0.476 |
| p-value | 0.544 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
