General Structure Information
| PDB ID | 3vkm |
| HGNC Gene Label(s) | LGALS8 |
| Structure Name | protease-resistant mutant form of human galectin-8 in complex with sialyllactose and lactose |
| Resolution | 2.98Å |
| Reference | AUTH H.YOSHIDA,S.YAMASHITA,M.TERAOKA,A.ITOH,S.NAKAKITA,N.NISHI,AUTH 2 S.KAMITORITITL X-RAY STRUCTURE OF A PROTEASE-RESISTANT MUTANT FORM OF HUMANTITL 2 GALECTIN-8 WITH TWO CARBOHYDRATE RECOGNITION DOMAINSREF FEBS J. V. 279 3937 2012REFN ISSN 1742-464XPMID 22913484DOI 10.1111/J.1742-4658.2012.08753.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 291 |
| Number Of SNVs | 88 |
| Number Of Permutations | 15582 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.048 |
| p-value | 0.478 |
COSMIC
| Number Of Residues | 291 |
| Number Of SNVs | 11 |
| Number Of Permutations | 10464 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.073 |
| p-value | 0.956 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 88 |
| Number Of COSMIC SNVs | 11 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.07 |
| p-value | 0.824 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
