General Structure Information
| PDB ID | 2p0r |
| HGNC Gene Label(s) | CAPN9 |
| Structure Name | structure of human calpain 9 in complex with leupeptin |
| Resolution | 2.5Å |
| Reference | AUTH T.L.DAVIS,R.PARAMANATHAN,J.R.WALKER,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURES OF HUMAN MINICALPAINS BOUND TO INHIBITORSREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 319 |
| Number Of SNVs | 99 |
| Number Of Permutations | 20527 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.617 |
COSMIC
| Number Of Residues | 319 |
| Number Of SNVs | 8 |
| Number Of Permutations | 2208 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.036 |
| p-value | 0.846 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 99 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.147 |
| p-value | 0.546 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
