General Structure Information
| PDB ID | 4gyy |
| HGNC Gene Label(s) | OGT |
| Structure Name | crystal structure of human o-glcnac transferase with udp-5sglcnac and a peptide substrate |
| Resolution | 1.85Å |
| Reference | AUTH M.B.LAZARUS,J.JIANG,T.M.GLOSTER,W.F.ZANDBERG,G.E.WHITWORTH,AUTH 2 D.J.VOCADLO,S.WALKERTITL STRUCTURAL SNAPSHOTS OF THE REACTION COORDINATE FOR O-GLCNACTITL 2 TRANSFERASE.REF NAT.CHEM.BIOL. V. 8 966 2012REFN ISSN 1552-4450PMID 23103939DOI 10.1038/NCHEMBIO.1109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 693 |
| Number Of SNVs | 28 |
| Number Of Permutations | 9350 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.04 |
| p-value | 0.844 |
COSMIC
| Number Of Residues | 693 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1503 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.095 |
| p-value | 0.782 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.23 |
| p-value | 0.727 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
