General Structure Information
| PDB ID | 2wnp |
| HGNC Gene Label(s) | FCN1 |
| Structure Name | m-ficolin mutant y271f |
| Resolution | 1.21Å |
| Reference | AUTH E.GOUT,V.GARLATTI,D.F.SMITH,M.LACROIX,AUTH 2 C.DUMESTRE-PERARD,T.LUNARDI,L.MARTIN,J.Y.CESBRON,AUTH 3 G.J.ARLAUD,C.GABORIAUD,N.M.THIELENSTITL CARBOHYDRATE RECOGNITION PROPERTIES OF HUMANTITL 2 FICOLINS: GLYCAN ARRAY SCREENING REVEALS THETITL 3 SIALIC ACID BINDING SPECIFICITY OF M-FICOLIN.REF J.BIOL.CHEM. V. 285 6612 2010REFN ISSN 0021-9258PMID 20032467DOI 10.1074/JBC.M109.065854 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 217 |
| Number Of SNVs | 55 |
| Number Of Permutations | 7454 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.214 |
COSMIC
| Number Of Residues | 217 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2095 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.133 |
| p-value | 0.365 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 55 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.061 |
| p-value | 0.796 |