General Structure Information
| PDB ID | 1q1z |
| HGNC Gene Label(s) | SULT2B1 |
| Structure Name | crystal structure of human cholesterol sulfotransferase (sult2b1b) in the presence of pap |
| Resolution | 2.4Å |
| Reference | AUTH K.A.LEE,H.FUDA,Y.C.LEE,M.NEGISHI,C.A.STROTT,AUTH 2 L.C.PEDERSENTITL CRYSTAL STRUCTURE OF HUMAN CHOLESTEROLTITL 2 SULFOTRANSFERASE (SULT2B1B) IN THE PRESENCE OFTITL 3 PREGNENOLONE AND 3-PHOSPHOADENOSINE 5-PHOSPHATE.TITL 4 RATIONALE FOR SPECIFICITY DIFFERENCES BETWEENTITL 5 PROTOTYPICAL SULT2A1 AND THE SULT2BG1 ISOFORMS.REF J.BIOL.CHEM. V. 278 44593 2003REFN ISSN 0021-9258PMID 12923182DOI 10.1074/JBC.M308312200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 284 |
| Number Of SNVs | 78 |
| Number Of Permutations | 7676 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.04 |
| p-value | 0.095 |
COSMIC
| Number Of Residues | 284 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3262 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.978 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 78 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.053 |
| p-value | 0.973 |