General Structure Information
| PDB ID | 1mv3 |
| HGNC Gene Label(s) | BIN1 |
| Structure Name | nmr structure of the tumor suppressor bin1: alternative splicing in melanoma and interaction with c-myc |
| Resolution | -1.0Å |
| Reference | AUTH A.PINEDA-LUCENA,C.S.HO,D.Y.MAO,Y.SHENG,R.C.LAISTER,AUTH 2 R.MUHANDIRAM,Y.LU,B.T.SEET,S.KATZ,T.SZYPERSKI,AUTH 3 L.Z.PENN,C.H.ARROWSMITHTITL A STRUCTURE-BASED MODEL OF THE C-MYC/BIN1 PROTEINTITL 2 INTERACTION SHOWS ALTERNATIVE SPLICING OF BIN1 ANDTITL 3 C-MYC PHOSPHORYLATION ARE KEY BINDING DETERMINANTS.REF J.MOL.BIOL. V. 351 182 2005REFN ISSN 0022-2836PMID 15992821DOI 10.1016/J.JMB.2005.05.046 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 213 |
| Number Of SNVs | 50 |
| Number Of Permutations | 66719 |
| Optimal Distance Threshold | 78.0 |
| K Statistic | 0.536 |
| p-value | 0.596 |