General Structure Information
| PDB ID | 2xik |
| HGNC Gene Label(s) | STK25 |
| Structure Name | structure of human ysk1 (yeast sps1-ste20-related kinase 1) |
| Resolution | 1.97Å |
| Reference | AUTH J.R.C.MUNIZ,P.RELLOS,M.VOLLMAR,C.ALLERSTON,A.CHAIKUAD,AUTH 2 P.SAVITSKY,G.BERRIDGE,B.BRENNER,J.M.ELKINS,N.DAGA,O.GILEADI,AUTH 3 P.MAHAJAN,B.SHRESTHA,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 4 J.WEIGELT,C.BOUNTRA,S.KNAPPTITL STRUCTURE OF HUMAN YSK1 (YEAST SPS1-STE20-RELATED KINASE 1)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 288 |
| Number Of SNVs | 57 |
| Number Of Permutations | 28002 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.226 |
| p-value | 0.218 |
COSMIC
| Number Of Residues | 288 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1437 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.071 |
| p-value | 0.521 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 57 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.13 |
| p-value | 0.483 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
