General Structure Information
| PDB ID | 1ekp |
| HGNC Gene Label(s) | BCAT2 |
| Structure Name | crystal structure of human branched chain amino acid aminotransferase (mitochondrial) complexed with pyridoxal-5-phosphate at 2.5 angstroms (monoclinic form). |
| Resolution | 2.5Å |
| Reference | AUTH N.YENNAWAR,J.DUNBAR,M.CONWAY,S.HUTSON,G.FARBERTITL THE STRUCTURE OF HUMAN MITOCHONDRIAL BRANCHED-CHAINTITL 2 AMINOTRANSFERASE.REF ACTA CRYSTALLOGR.,SECT.D V. 57 506 2001REFN ISSN 0907-4449PMID 11264579DOI 10.1107/S0907444901001925 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 365 |
| Number Of SNVs | 91 |
| Number Of Permutations | 37357 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.04 |
| p-value | 0.176 |
COSMIC
| Number Of Residues | 365 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1041 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.143 |
| p-value | 0.337 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 91 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.07 |
| p-value | 0.377 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
