General Structure Information
| PDB ID | 4hdo |
| HGNC Gene Label(s) | KRIT1 |
| Structure Name | crystal structure of the binary complex of krit1 bound to the rap1 gtpase |
| Resolution | 1.67Å |
| Reference | AUTH A.R.GINGRAS,W.PUZON-MCLAUGHLIN,M.H.GINSBERGTITL THE STRUCTURE OF THE TERNARY COMPLEX OF KREV INTERACTIONTITL 2 TRAPPED 1 (KRIT1) BOUND TO BOTH THE RAP1 GTPASE AND THETITL 3 HEART OF GLASS (HEG1) CYTOPLASMIC TAIL.REF J.BIOL.CHEM. V. 288 23639 2013REFN ISSN 0021-9258PMID 23814056DOI 10.1074/JBC.M113.462911 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 310 |
| Number Of SNVs | 75 |
| Number Of Permutations | 34681 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.034 |
| p-value | 0.536 |
COSMIC
| Number Of Residues | 310 |
| Number Of SNVs | 3 |
| Number Of Permutations | 169 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | 0.333 |
| p-value | 0.53 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
