General Structure Information
| PDB ID | 3o35 |
| HGNC Gene Label(s) | TRIM24 |
| Structure Name | crystal structure of trim24 phd-bromo complexed with h3(23-31)k27ac peptide |
| Resolution | 1.76Å |
| Reference | AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 178 |
| Number Of SNVs | 15 |
| Number Of Permutations | 6281 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.0 |
| p-value | 0.457 |
COSMIC
| Number Of Residues | 178 |
| Number Of SNVs | 5 |
| Number Of Permutations | 363 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.4 |
| p-value | 0.458 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 15 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.381 |
| p-value | 0.287 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
