General Structure Information
| PDB ID | 2c0j |
| HGNC Gene Label(s) | TRAPPC3 |
| Structure Name | crystal structure of the bet3-trs33 heterodimer |
| Resolution | 2.2Å |
| Reference | AUTH M.-S.KIM,M.-J.YI,K.-H.LEE,J.WAGNER,C.MUNGER,Y.-G.KIM,AUTH 2 M.WHITEWAY,M.CYGLER,B.-H.OH,M.SACHERTITL BIOCHEMICAL AND CRYSTALLOGRAPHIC STUDIES REVEAL A SPECIFICTITL 2 INTERACTION BETWEEN TRAPP SUBUNITS TRS33P AND BET3PREF TRAFFIC V. 6 1183 2005REFN ISSN 1398-9219PMID 16262728DOI 10.1111/J.1600-0854.2005.00352.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 161 |
| Number Of SNVs | 27 |
| Number Of Permutations | 3407 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.037 |
| p-value | 0.975 |
COSMIC
| Number Of Residues | 161 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.667 |
| p-value | 0.011 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 27 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.903 |
| p-value | 0.005 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
