General Structure Information
| PDB ID | 4c0d |
| HGNC Gene Label(s) | CNOT1 |
| Structure Name | structure of the not module of the human ccr4-not complex (cnot1-cnot2-cnot3) |
| Resolution | 3.2Å |
| Reference | AUTH A.BOLAND,Y.CHEN,T.RAISCH,S.JONAS,D.KUZUOGLU-OZTURK,AUTH 2 L.WOHLBOLD,O.WEICHENRIEDER,E.IZAURRALDETITL STRUCTURE AND ASSEMBLY OF THE NOT MODULE OF THE HUMANTITL 2 CCR4-NOT COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1289 2013REFN ISSN 1545-9993PMID 24121232DOI 10.1038/NSMB.2681 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 512 |
| Number Of SNVs | 42 |
| Number Of Permutations | 35177 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.201 |
| p-value | 0.079 |
COSMIC
| Number Of Residues | 512 |
| Number Of SNVs | 11 |
| Number Of Permutations | 10372 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.018 |
| p-value | 0.753 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 41.0 |
| K Statistic | 0.177 |
| p-value | 0.564 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
