General Structure Information
| PDB ID | 4o7q |
| HGNC Gene Label(s) | AIM2 |
| Structure Name | crystal structure of the f27g aim2 pyrin domain mutant and similarities of its self-association to ded/ded interactions |
| Resolution | 1.82Å |
| Reference | AUTH A.LU,V.KABALEESWARAN,T.FU,V.G.MAGUPALLI,H.WUTITL CRYSTAL STRUCTURE OF THE F27G AIM2 PYD MUTANT ANDTITL 2 SIMILARITIES OF ITS SELF-ASSOCIATION TO DED/DEDTITL 3 INTERACTIONS.REF J.MOL.BIOL. V. 426 1420 2014REFN ISSN 0022-2836PMID 24406744DOI 10.1016/J.JMB.2013.12.029 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 93 |
| Number Of SNVs | 21 |
| Number Of Permutations | 5352 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.152 |
| p-value | 0.403 |
COSMIC
| Number Of Residues | 93 |
| Number Of SNVs | 3 |
| Number Of Permutations | 133 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.667 |
| p-value | 0.537 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
