General Structure Information
| PDB ID | 4nxt |
| HGNC Gene Label(s) | MIEF1 |
| Structure Name | crystal structure of the cytosolic domain of human mid51 |
| Resolution | 2.12Å |
| Reference | AUTH V.RICHTER,C.S.PALMER,L.D.OSELLAME,A.P.SINGH,K.ELGASS,AUTH 2 D.A.STROUD,H.SESAKI,M.KVANSAKUL,M.T.RYANTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF MID51, A DYNAMINTITL 2 RECEPTOR REQUIRED FOR MITOCHONDRIAL FISSION.REF J.CELL BIOL. V. 204 477 2014REFN ISSN 0021-9525PMID 24515348DOI 10.1083/JCB.201311014 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 331 |
| Number Of SNVs | 91 |
| Number Of Permutations | 20159 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.021 |
| p-value | 0.023 |
COSMIC
| Number Of Residues | 331 |
| Number Of SNVs | 7 |
| Number Of Permutations | 3350 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.095 |
| p-value | 0.818 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 91 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.056 |
| p-value | 0.847 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
