General Structure Information
| PDB ID | 4nt5 |
| HGNC Gene Label(s) | VWF |
| Structure Name | crystal structure of human von willebrand factor ctck domain |
| Resolution | 3.28Å |
| Reference | AUTH Y.F.ZHOU,T.A.SPRINGERTITL HIGHLY REINFORCED STRUCTURE OF A C-TERMINAL DIMERIZATIONTITL 2 DOMAIN IN VON WILLEBRAND FACTOR.REF BLOOD V. 123 1785 2014REFN ISSN 0006-4971PMID 24394662DOI 10.1182/BLOOD-2013-11-523639 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 93 |
| Number Of SNVs | 22 |
| Number Of Permutations | 4102 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.346 |
| p-value | 0.09 |
COSMIC
| Number Of Residues | 93 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
