General Structure Information
| PDB ID | 4m6t |
| HGNC Gene Label(s) | LEO1 |
| Structure Name | structure of human paf1 and leo1 complex |
| Resolution | 2.5Å |
| Reference | AUTH X.CHU,X.QIN,H.XU,L.LI,Z.WANG,F.LI,X.XIE,H.ZHOU,Y.SHEN,J.LONGTITL STRUCTURAL INSIGHTS INTO PAF1 COMPLEX ASSEMBLY AND HISTONETITL 2 BINDINGREF NUCLEIC ACIDS RES. V. 41 10619 2013REFN ISSN 0305-1048PMID 24038468DOI 10.1093/NAR/GKT819 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 87 |
| Number Of SNVs | 9 |
| Number Of Permutations | 871 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.14 |
COSMIC
| Number Of Residues | 87 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.421 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 9 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.222 |
| p-value | 0.891 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
