General Structure Information
| PDB ID | 4m0a |
| HGNC Gene Label(s) | POLM |
| Structure Name | human dna polymerase mu post-catalytic complex |
| Resolution | 1.85Å |
| Reference | AUTH A.F.MOON,J.M.PRYOR,D.A.RAMSDEN,T.A.KUNKEL,K.BEBENEK,AUTH 2 L.C.PEDERSENTITL SUSTAINED ACTIVE SITE RIGIDITY DURING SYNTHESIS BY HUMAN DNATITL 2 POLYMERASE MU.REF NAT.STRUCT.MOL.BIOL. V. 21 253 2014REFN ISSN 1545-9993PMID 24487959DOI 10.1038/NSMB.2766 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 325 |
| Number Of SNVs | 90 |
| Number Of Permutations | 13481 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.074 |
| p-value | 0.041 |
COSMIC
| Number Of Residues | 325 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1054 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.067 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 90 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.108 |
| p-value | 0.765 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
