General Structure Information
| PDB ID | 4lqy |
| HGNC Gene Label(s) | ENPP4 |
| Structure Name | crystal structure of human enpp4 with amp |
| Resolution | 1.54Å |
| Reference | AUTH R.A.ALBRIGHT,D.L.ORNSTEIN,W.CAO,W.C.CHANG,D.ROBERT,M.TEHAN,AUTH 2 D.HOYER,L.LIU,P.STABACH,G.YANG,E.M.DE LA CRUZ,D.T.BRADDOCKTITL MOLECULAR BASIS OF PURINERGIC SIGNAL METABOLISM BYTITL 2 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASES 4 AND 1TITL 3 AND IMPLICATIONS IN STROKE.REF J.BIOL.CHEM. V. 289 3294 2014REFN ISSN 0021-9258PMID 24338010DOI 10.1074/JBC.M113.505867 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 379 |
| Number Of SNVs | 86 |
| Number Of Permutations | 14919 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.041 |
| p-value | 0.342 |
COSMIC
| Number Of Residues | 379 |
| Number Of SNVs | 9 |
| Number Of Permutations | 8483 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.028 |
| p-value | 0.642 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 86 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.051 |
| p-value | 0.758 |