General Structure Information
| PDB ID | 4kmz |
| HGNC Gene Label(s) | FOLR2 |
| Structure Name | human folate receptor beta (folr2) in complex with the folate |
| Resolution | 2.3Å |
| Reference | AUTH A.S.WIBOWO,M.SINGH,K.M.REEDER,J.J.CARTER,A.R.KOVACH,W.MENG,AUTH 2 M.RATNAM,F.ZHANG,C.E.DANNTITL STRUCTURES OF HUMAN FOLATE RECEPTORS REVEAL BIOLOGICALTITL 2 TRAFFICKING STATES AND DIVERSITY IN FOLATE AND ANTIFOLATETITL 3 RECOGNITION.REF PROC.NATL.ACAD.SCI.USA V. 110 15180 2013REFN ISSN 0027-8424PMID 23934049DOI 10.1073/PNAS.1308827110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 203 |
| Number Of SNVs | 53 |
| Number Of Permutations | 15559 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.06 |
| p-value | 0.103 |
COSMIC
| Number Of Residues | 203 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1113 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.1 |
| p-value | 0.762 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.288 |
| p-value | 0.316 |