General Structure Information
| PDB ID | 4k8a |
| HGNC Gene Label(s) | PTK2 |
| Structure Name | fragment-based discovery of focal adhesion kinase inhibitors |
| Resolution | 2.91Å |
| Reference | AUTH U.GRADLER,J.BOMKE,D.MUSIL,V.DRESING,M.LEHMANN,G.HOLZEMANN,AUTH 2 H.GREINER,C.ESDAR,M.KRIER,T.HEINRICHTITL FRAGMENT-BASED DISCOVERY OF FOCAL ADHESION KINASETITL 2 INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 23 5401 2013REFN ISSN 0960-894XPMID 23973211DOI 10.1016/J.BMCL.2013.07.050 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 258 |
| Number Of SNVs | 37 |
| Number Of Permutations | 18794 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.027 |
| p-value | 0.786 |