General Structure Information
| PDB ID | 4js0 |
| HGNC Gene Label(s) | CDC42 |
| Structure Name | complex of cdc42 with the crib-pr domain of irsp53 |
| Resolution | 1.9Å |
| Reference | AUTH D.J.KAST,C.YANG,A.DISANZA,M.BOCZKOWSKA,Y.MADASU,G.SCITA,AUTH 2 T.SVITKINA,R.DOMINGUEZTITL MECHANISM OF IRSP53 INHIBITION AND COMBINATORIAL ACTIVATIONTITL 2 BY CDC42 AND DOWNSTREAM EFFECTORS.REF NAT.STRUCT.MOL.BIOL. V. 21 413 2014REFN ISSN 1545-9993PMID 24584464DOI 10.1038/NSMB.2781 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 178 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1320 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.5 |
| p-value | 0.007 |