General Structure Information
| PDB ID | 4jgh |
| HGNC Gene Label(s) | SOCS2 |
| Structure Name | structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5 |
| Resolution | 3.0Å |
| Reference | AUTH Y.K.KIM,M.J.KWAK,B.KU,H.Y.SUH,K.JOO,J.LEE,J.U.JUNG,B.H.OHTITL STRUCTURAL BASIS OF INTERSUBUNIT RECOGNITION IN ELONGINTITL 2 BC-CULLIN 5-SOCS BOX UBIQUITIN-PROTEIN LIGASE COMPLEXES.REF ACTA CRYSTALLOGR.,SECT.D V. 69 1587 2013REFN ISSN 0907-4449PMID 23897481DOI 10.1107/S0907444913011220 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 157 |
| Number Of SNVs | 19 |
| Number Of Permutations | 2237 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.029 |
| p-value | 0.453 |
COSMIC
| Number Of Residues | 157 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 0.778 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 19 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.444 |
| p-value | 0.294 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
