4J19.B | HMBOX1

General Structure Information

PDB ID 4j19
HGNC Gene Label(s) HMBOX1
Structure Name structure of a novel telomere repeat binding protein bound to dna
Resolution 2.9Å
Reference AUTH D.KAPPEI,F.BUTTER,C.BENDA,M.SCHEIBE,I.DRASKOVIC,M.STEVENSE,AUTH 2 C.L.NOVO,C.BASQUIN,M.ARAKI,K.ARAKI,D.B.KRASTEV,R.KITTLER,AUTH 3 R.JESSBERGER,J.A.LONDONO-VALLEJO,M.MANN,F.BUCHHOLZTITL HOT1 IS A MAMMALIAN DIRECT TELOMERE REPEAT-BINDING PROTEINTITL 2 CONTRIBUTING TO TELOMERASE RECRUITMENT.REF EMBO J. V. 32 1681 2013REFN ISSN 0261-4189PMID 23685356DOI 10.1038/EMBOJ.2013.105

Variant Set Distributions

ExAC Variants

Number Of Residues 76
Number Of SNVs 6
Number Of Permutations 646
Optimal Distance Threshold 14.0
K Statistic 0.2
p-value 0.302

Mapped Variants

[+] ExAC Missense Variants